Ambulatory high-resolution manometry, lower esophageal sphincter lift and transient lower esophageal sphincter relaxation

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Upper esophageal sphincter during transient lower esophageal sphincter relaxation: effects of reflux content and posture.

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Ambulatory pH-recording is one of the key diagnostic studies in gastroesophageal reflux disease. It is recommended that the pH-probe is inserted 5 cm above the proximal border of the lower esophageal sphincter (LES) and the latter should be determined optimally with manometry [1]. However, some studies have shown that the pH step-up especially done in the supine position could be almost as accu...

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[Transient lower esophageal sphincter relaxation and the related esophageal motor activities].

Transient lower esophageal sphincter (LES) relaxation (TLESR) is defined as LES relaxation without a swallow. TLESRs are observed in both of the normal individuals and the patients with gastroesophageal reflux disorder (GERD). However, TLESR is widely considered as the major mechanism of the GERD. The new equipments such as high resolution manometry and impedance pH study is helped to understan...

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ژورنال

عنوان ژورنال: Neurogastroenterology & Motility

سال: 2011

ISSN: 1350-1925

DOI: 10.1111/j.1365-2982.2011.01816.x